MycoReal Candida

 

MycoReal CandidaMycoReal Aspergillus

 

 

Background: Candidiasis is a yeast infection caused by different Candida species. Candida can cause opportunistic infections of the skin and mucosa as well invasive infections. Candida albicans formerly being the most important species, is still the one most often species causing diseases. However, other species than C. albicans, in particular C. glabrata, but also C. tropicalis, C. krusei, C. parapsilosis, C. dubliniensis and C. lusitaniae have gained greater clinical significance.Invasive fungal infections are increasingly recognized as a primary cause of morbidity and mortality especially in immunocompromised patients. The early diagnosis improves prognosis. Candida-PCR gains more and more importance in the diagnosis of a Candida-infection.

MycoReal Candida is a real-time PCR detection assay for rapid and sensitive detection as well as differentiation of 7 medically important species of Candida (C. albicans, C. dubliniensis, C. glabrata, C. krusei, C. lusitaniae, C. parapsilosis and C. tropicalis). Species can be differentiated by specific melting curves. By using species-specific probes the test is highly specific for Candida. The identification of the species allows a first conclusion on a possible antimycotica resistance behaviour.

Since MycoReal Assays (MycoReal Aspergillus, MycoReal Candida, MycoReal Pneumocystis and MycoReal Fungi) use identical temperature/time profiles, they can be combined in the same LightCycler® run. This allows the detection of a wide panel of pathogenic fungi within only a few hours.

Product MycoReal Candida
Order no. RTPM200
Unit 50 reactions
CE-IVD No
Technology Real-time PCR
Content Assay Candida
Assay internal positive control
Positive controls for C. albicans and C. krusei
Internal positive control
Water
Manual (for LightCycler® 2.0)
Attention: Amplification mix is not included, see product description
Target gene ITS-2 region
Detection 610 nm, 640 nm, 670 nm, 705 nm
PCR-platform LightCycler® 2.0 
Additionally required PCR-reagents  LC™-FastStart DNA Master Kit Hybridisation Probes 
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